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Alaffia Health taps AI to detect errors in hospital bills • ZebethMedia

The multi-decade rise in healthcare costs isn’t expected to reverse course any time soon. In search of a fix, Adun Akanni and TJ Ademiluyi co-founded Alaffia Health in 2020, one of the startups participating in the ZebethMedia Disrupt Battlefield 200. The healthtech company uses machine learning to try to identify fraud, waste and abuse in healthcare claims. “We leveraged key insights from our family’s medical billing company in founding Alaffia,” Ademiluyi told ZebethMedia in an interview. “We determined that the majority of the waste in the system results from natural human error, lack of transparency in claims processing, and misaligned incentives between healthcare providers and payers. We founded Alaffia to tackle these issues using nascent machine learning and AI, built on top of deep healthcare domain expertise.” Alaffia sells services primarily to health insurance payers and enterprises that provide their employees health coverage. Using AI to extract and standardize data from hospital bills, including various medical billing procedure codes and dates of service, the platform aims to reduce payers’ spending by finding errors and overcharges within the bills sent by healthcare providers. The causes of medical billing errors are myriad, but often arise from double billing, missing the payer submission deadline and a failure to capture patient information. Non-specific diagnostic codes are another common issue, leading to instances of upcoding and undercoding. Upcoding is when a coder reports a higher-level service than patients received or never had performed, while undercoding is when billing codes don’t capture the full scope of work performed by a physician. Medical expenses are expected to grow by an average of 5.1% from 2021 to 2030, reaching $6.8 trillion, according to the Centers for Medicare and Medicaid Services — and a significant portion of those expenditures are derived from errors in health insurance claims. It’s estimated that about 80% of claims in the U.S. contain at least one medical billing error, and that as much as $300 billion is lost to provider fraud, waste and abuse each year. Image Credits: Alaffia Health “This is a quite challenging technical problem due to the lack of data standardization in the healthcare system, so we’ve rigorously trained machine learning models using training data generated by our in-house annotation team,” Ademiluyi said. Alaffia reviews facility bills for errors such as “unbundling” — i.e., using multiple codes for individual parts of a procedure — while checking the accuracy of more complex claims like implants and surgeries. The company says it taps registered nurses, certified coders and certified billers to cross-reference the AI’s findings, as well as a clinical review team that examines each claim and corresponding medical record. When asked about competitors, Ademiluyi says he sees “legacy industry participants” who manually process and review claims as Alaffia’s principal rivals. But Alaffia isn’t the only startup attempting to tackle the medical billing error problem with AI. Anomaly, which works with insurance companies and providers, offers an AI-driven platform designed to detect irregularities in medical bills. There’s also Nym, whose technology converts medical charts and electronic medical records from physician consultations into auditable billing codes automatically. Alaffia has managed to gain traction in the space, however — and funding. Ademiluyi claims the company’s services currently cover over 300,000 health plan members in aggregate. And to date, Alaffia has raised $6.6 million in venture capital from backers including Anthemis, 1984 Ventures, Aperture Venture Capital, Tau Ventures, Twine Ventures, Plug and Play Ventures and ERA’s Remarkable Ventures Fund. Ademiluyi says that 2022 revenue is on pace to more than double year-over-year. The near-term plan is to expand Alaffia’s commercial footprint and product offerings, he added, starting with hospital bill review services direct to patients. The company currently employs “just over” 20 people and expects to hire five more by the end of the year. “Fortunately, we operate in an industry resistant to recession. Regardless of pandemics, macro trends, or the outlook for interest rates, people will still visit the doctor to receive care,” Ademiluyi said. “When patients receive care, it leads to further healthcare spending, which benefits our business as we review generated hospital bills for errors. As we move into a slowdown in the market, large enterprises — both health insurance institutions and employers whom we support are actually looking at ways to lower their expenses, which we directly support by reducing healthcare spending. As such, we believe the pandemic and current slowdown in the economy to be a net positive for the business.”

Vitag launches NFC-powered ‘sticky notes’ for visual instructions • ZebethMedia

While QR codes emerged as something of a technology poster-child during the pandemic, garnering a new lease of life in everything from restaurant menus to contactless payments, there remains a certain inelegance to the matrix barcode system. Usability remains a sticking point, both in terms of the effort it takes to create content and align it with a QR code, and also from the end-user’s standpoint who has to open their camera app to scan the QR code — something that might not even work in low-light situations. Throw into the mix aesthetics (who’s ever seen an attractive QR code?), and there’s a strong case to be made for an alternative that brings the QR code spirt to a more user friendly format. This is a problem that Vitag is setting out to address, with an NFC product designed for video instructions. Or, “video sticky notes,” as the company calls them. Founded in Dallas in March this year, Vitag is officially announcing its private beta today at TC Disrupt, where the company was selected as one of ZebethMedia’s Battlefield 200 startup cohorts. We caught up with cofounders Sean Jackson (CEO) and CTO Daniel Reiling to get a sneak peek into what exactly it’s looking to achieve. Vitag cofounders: Daniel Reiling (CTO) and Sean Jackson (CEO) Image Credits: ZebethMedia Videos on tap Vitag’s product consists of two core “things”: a mobile app for people to record instructional videos or upload existing material from their device, and a physical NFC-enabled tag that they can program the video to. All the end-user then has to do is tap their phone on the tag, and the video pops up on their screen, demonstrating to an AirBnb guest how to use the A/C system or where the recycling goes. Vitag in action Image Credits: Vitag Of course, it’s easy enough to achieve all this through QR codes — there are many online services for generating QR codes which someone can then tether to a YouTube video that they created. What Vitag does, though, is provide the tools for creating the video, managing tags, and hosting the actual video itself — it has built its own hosting service on top of Google Cloud, with the content viewable only to those with access to a unique URL, which is activated when users tap their phone to a tag. “We created our own service where you can capture a video on your phone, it goes to our servers, and it’s hosted there,” Reiling said. It may seem more intuitive to have just used an existing white-label video hosting service from a company like Vimeo, but the founders explained its reasoning for building its own hosting service: it’s about scalability, controllability, and customizability. While Vimeo might be great for a company to host its own videos, when it comes to potentially hundreds or thousands of Vitag’s own customers who need their own individual accounts for creating and storing hundreds or thousands of videos, this requires full control of the experience from creation through to hosting. The entire back-end and front-end packaged in a single platform. “Our goal is to remove complexity from the process of sharing instructions,” Jackson said. “We believe people are tired of cobbling together different technologies to complete a task — from QR code generators, to different hosting platforms, to desktop publishing tools, to printers, to adhesives — and everything else required.” However, it’s not purely about video. A customer can configure their tag so that it links to a static text page, a photo, URL, or whatever they want. The company offers $2 pre-printed tags specific to a certain type of business, for example restaurants or retail, while creators can also order personalized tags with their own individual text and a choice of different backgrounds. It’s also worth noting that companies can elect to have QR codes printed on the NFC tags for those who prefer to use QR codes, Vitag: Customization interface Image Credits: ZebethMedia Furthermore, Vitag also supports NFC tags from third-party providers, with an in-app function for users to format the tags to work with Vitag. The company said that it’s also planning additional tools in the future, including a desktop app with additional features for small businesses and enterprise customers. NFC surge NFC, or near-field communication as it’s more formally known, is hardly a new technology, but it has taken its time to properly hit the mainstream consciousness, where it still pretty much resides in the payments domain. But its recent growth has been aided somewhat by recent adoption from big tech companies such as Apple, which started to fully embrace NFC with iOS 13 back in 2019 — instead of only allowing iPhone apps to read NFC tags, Apple started to allow apps to write directly to blank tags, and interact through native protocols. The company also recently launched a new “tap to pay” feature that allows iPhones to accept contactless payments over NFC. Elsewhere, NFC is also being used as a replacement for business cards, allowing people to exchange information just by tapping phones. So while QR codes have seen a major resurgence in recent years and are unlikely to being going away any time soon, NFC is on something of an upwards trajectory too, which is where Vitag wants to make its mark. “We believe that consumers are becoming more comfortable with ‘tap to’ events, with payments being the most used today,” Jackson said. “And as more people become exposed to digital business cards the market adoption of ‘tap to’ will only increase.” For now, Vitag is looking to serve the short-term rental property market in the U.S., which Jackson identified as a particularly powerful use-case for video instructions. But plans are afoot to target all manner of verticals, from restaurants and retail stores to gyms. “As we shared our vision of what this technology could do, we found use-case after use-case from almost everyone we encountered,” Jackson explained. “People that stayed in rentals wanted to use them

‘Investors got scared off by Amazon’s attack’ • ZebethMedia

Way back in 2010, Marc Lore struck a more than half-a-billion dollar deal to sell Quidsi — the company behind Diapers.com and Soap.com — to Amazon. The blow-out acquisition helped turn Amazon into “the everything store,” but twelve years later, Lore described the sale as “upsetting.” “We sold out,” said Lore — who co-founded both Quidsi.com and Jet.com — at Disrupt 2022. “With Walmart, we were happy to sell; we saw that as a way to accelerate our vision,” said the billionaire of the 2016 sale of Jet.com to Walmart. The “Amazon situation was different. It was a forced situation. We did not want to sell,” Lore said on stage in conversation with ZebethMedia’s Ingrid Lunden. To stick it to the competition, Amazon “cut the price of diapers by 30%, right? Which is unheard of,” recalled Lore. But in the face of ratcheting pressure, the former Quidsi executive claimed his now-defunct business was “still growing nicely.” Lore claimed this was among the reasons why Amazon ultimately decided snapped up the brand. But before that point, Lore believed that Quidsi needed to raise at least $100 million more to adequately challenge Amazon— an especially hefty sum at the time. Only, he couldn’t secure it. (In all, Quidsi raised around $79 million in equity and debt from investors, including Accel, Bessemer Venture Partners and Pinnacle Ventures.) “That’s what it would have taken to feel like we had enough capital to really do it,” said Lore. “And yeah, the investors got scared off by Amazon’s attack.” In a side note, Lore claimed that Quidsi also “had an offer from another company” for “like $100 million more,” yet the co-founder enigmatically declined to share additional details. A day after the Amazon-Quidsi transaction closed, Lore said that he and others from the company went to a bar, “drinking our tears away” over “how upsetting it was, because we sold out.” “We were building something really special,” Lore added, citing Wag.com and other sites under the now-extinct Quidsi umbrella. In the eyes of the co-founder, Quidsi’s customer experience back then “was a lot better than you’d find on Amazon or anywhere else.” But $100 million “was a lot of money” back then, and Lore concluded: “People were just scared of Amazon.”

a16z GP on investing billions in Adam Neumann • ZebethMedia

Andreessen Horowitz (a16z) general partner Chris Dixon shed some light on the firm’s recent investments in controversial WeWork founder Adam Neumann on stage at ZebethMedia Disrupt 2022. Neumann raised $350 billion from the venture firm back in August in a deal that reportedly valued his new real estate venture, Flow, at $1 billion before it had even launched. That investment, which marked the largest check a16z had ever written for a single company and its second bet on a Neumann startup in 2022, drew criticism from VCs and founders. Many noted Neumann’s less-than-ideal track record at WeWork, which under his tenure tanked in value from ~$47 billion to ~$8 billion and gained a reputation for mismanagement and poor treatment of employees. Marc Andreessen, the venture firm’s founder who led the Flow deal, saw Neumann’s track record differently, Dixon told interviewer Lucas Matney. “He’s one of the few founders — I mean, he’s one of the only people in the world who has built a real estate brand name,” Dixon said. The funding news in August also came on the heels of the release of WeCrashed, an Apple TV+ show that depicted Neumann’s rise, fall and exit from WeWork with actor Jared Leto playing the founder. The show, which portrayed Neumann as a narcissistic, chaotic leader, was inspired by actual events but did not purport to be a documentary. “I know there’s a lot of stuff written about [Neumann] and things we did, but we do our own research. We just don’t rely on books and movies for our diligence. We do our own research, and we just came to a different conclusion on a lot of what happened,” Dixon said.

Code analysis tool AppMap wants to become Google Maps for developers • ZebethMedia

In December 2021, a vulnerability in a widely used logging library that had gone unfixed since 2013 caused a full-blown security meltdown.  The 10/10-rated Log4Shell flaw in Log4j, an open source logging software that’s found practically everywhere, from online games to enterprise software and cloud data centers, claimed numerous victims from Adobe and Cloudflare to Twitter and Minecraft due to its ubiquitous presence. It was described by security experts as a “design failure of catastrophic proportions,” and demonstrated the potentially far-reaching consequences of shipping bad code. Boston-based AppMap, going through ZebethMedia Disrupt Startup Battlefield this week, wants to stop this bad code from ever making it into production. The open source dynamic runtime code analysis tool, which the startup claims is the first of its kind, is the brainchild of Elizabeth Lawler, who knows a thing or two about security. Prior to founding AppMap, she founded DevOps security startup Conjur, which was acquired by CyberArk in 2017, and served as chief data officer for Generation Health, later acquired by CVS. After selling two companies into large enterprises with lots of legacy software, Lawler witnessed firsthand how developers were struggling to understand the systems they were tasked with improving, and finding it difficult to deliver fast and secure code in complex microservices and cloud applications. “It’s surprising to me that people have a mental model of how things work that is actually disconnected from how it actually works,” Lawler tells ZebethMedia. “When we don’t know how our software works, we’re making best guesses when we write code.”  Image Credits: AppMap That led to the creation of AppMap, which was built on the simple idea that developers should be able to see the behavior of software as they write it so they can prevent problems when the software runs. Unlike static analysis tools that don’t show runtime information, AppMap — which was built from the ground up over a three-year period — runs within the code editor to show developers which components are communicating with which components, at what throughput and latency, at what network speed and whether there are any errors between them, enabling developers to get actionable insights and make improvements quicker than before. All of this is done within an interactive code editor extension, which AppMap designed with the help of comic book artists and musicians in order to make it as easy to use and intuitive as possible.  “I’m a data scientist, so I know how overwhelming data can be,” said Lawler. “Google Maps has elegantly shown us how maps can be personalized and localized, so we used that as a jumping off point for how we wanted to approach the big data problem.” To coincide with ZebethMedia Disrupt, AppMap is launching three new features: the ability to share and collaborate with other engineers; performance analysis that alerts developers when code changes will impact performance and scalability; and security analysis that can identify software runtime code issues within a developer’s code editor before they commit their code, be it leaking customer data and secrets into log files or missing or improper authentication or authorization. “We can see the kinds of issues that are now the rising OWASP Top 10. Static issues have gone down in prevalence because we have good scanners for them, but what we don’t have great scanners for are these dynamic issues that are design in nature. If you look at the CWE Top 25, almost half of these are code design issues.” As it’s based on open source, which is evident from the startup’s community-sourced approach to changing its product and adding new features, AppMap is free for developers to use. “We don’t believe you should be charged for self-awareness in programming,” Lawler said. “If we’re going to integrate with your GitHub and we have to provide some background functions or storage, then those are paid services.” Image Credits: AppMap AppMap, which is a seed-stage VC-backed pre-revenue startup, currently has more than 20,000 customers — a figure that’s growing by 20% every month — with developers at IBM, NASA, Sonos and Salesforce using its product. It’s also growing its team, which is made up of employees that have coded at some point in their career and hold deep DevOps, automation, cybersecurity and test-driven development experience. Kevin Gilpin, AppMap’s technical co-founder, describes his career highlight as delivering “build your vehicle online” pages for Ford.  Though it only launched in 2021, the startup’s vision goes far beyond preventing developers from shipping bad code. “We spend a lot of time and energy instrumenting things that are downstream of our application, but we’ve never instrumented the creative process. We’ve never really watched people think, design and create in this way. I think that by having observability data in that moment, it’s going to open up a lot of opportunities. As AppMap evolves, I’d like to think about how this gets even bigger than performance analysis and becomes more of an assistive technology in that realm.”

a16z’s Chris Dixon announces new accelerator program for crypto founders in LA • ZebethMedia

Andreessen Horowitz (a16z) is one of the most influential players in the web3, funding entrepreneurs in the space amid “crypto winter.” Founded and helmed by general partner Chris Dixon, the venture firm’s crypto arm raised a massive $4.5 billion fund in May for its fourth dedicated sector fund to continue backing early-stage founders just as the crypto downturn had begun to take root. Now, it’s doubling down on its programming for crypto founders, Dixon, an early Coinbase backer who has been investing at a16z since 2012, revealed on stage at Disrupt 2022 in San Francisco on Tuesday in an interview with ZebethMedia’s Lucas Matney. On stage, Dixon announced a16z’s plans to expand its educational “Crypto Startup School” initiative to include a new accelerator program for entrepreneurs. The inaugural accelerator program will take place in-person in March in Los Angeles, Dixon said, adding that he has noticed particular excitement in the city around the creator economy and its potential intersections with crypto. Participants in the 12-week program will each get $500k in seed funding and access to mentors and advisors as well as the opportunity to participate in a Demo Day at the end of the course, according to the website. Applications for the accelerator are now open, Dixon said, though he did not share details on the expected cohort size. “This one will be different than the last one in that we will also provide capital and take equity, similar to an accelerator and Startup School combined,” Dixon said of the new program, contrasting it with the current version of “Crypto Startup School.” “Crypto Startup School” first launched in 2020 as a seven-week course meant to educate people on how to build a crypto company. The in-person cohort had 40 founders participating, including those behind companies such as Phantom and Notional Finance, and raised a collective $300 million+ in venture funding, according to a16z. a16z Crypto also released video segments of its lectures for the public to view, which it says have been watched by over 1 million people. Instructors for the first program included Dixon, Stanford computer science professor Dan Boneh, Coinbase founder Brian Armstrong and other well-known industry leaders. Dixon noted that the new program will remain crypto-focused and that a16z is “not trying to build some sort of new startup accelerator,” saying the new offering is instead intended to be an educational program with funding that is tied to the “very specific” sector. When asked about what makes the firm’s offering unique from accelerators such as Y Combinator, Dixon said there isn’t a “grand master plan” for this launch and that it was built as a response to feedback he had been hearing from founders. “We literally just meet entrepreneurs all the time, who say, hey, I wish that conversation we had was available online … so we’re just listening [to them],” Dixon said.

Anthill connects frontline workers to company resources through text messaging • ZebethMedia

If the pandemic has made us completely rethink the way we work, that we — the swath of workers at home in pajamas popping into meetings on Zoom — leaves out a massive chunk of the workforce that continues to show up for work in-person, every time. As knowledge workers explore the intricacies of the virtual office, frontline workers from a cross-section of critical industries still lack the basic tools they need to do simple tasks like switching shifts, asking HR a question or seeing when their next paycheck arrives. “This workforce can’t be overlooked, there is a business imperative right now…[and] there is a really exciting opportunity to create more paths to the middle class,” Anthill co-founder and CEO Muriel Clauson told ZebethMedia. Clauson and Anthill co-founder and CTO Young-Jae Kim met in a PhD program for industrial and organizational psychology at the University of Georgia. Through their shared academic research interests, they identified what Clauson described as a “massive gap” in the communication between frontline, deskless workers and their employers — a gap that workers frequently fall into, to everyone’s detriment: [There are] 2.7 billion people globally, who never sit at computers to do their jobs. So they never worked from home over the pandemic and they never will because they can’t actually do their job that way. So most often folks think of manufacturing, distribution — basically anybody who’s out there working with their hands on the field on the floor. These folks do not use software, and especially work software, they just in general do not and the reason being is they’re not sitting at computers, they’re not going to use something on a desktop. They’re probably not using email [and] they probably don’t even have an email address. And they’re also increasingly not downloading or using apps on their phone — or they don’t even have a phone that you can use an app on. For employers who manage an in-person workforce, attrition is a huge issue. Many workers aren’t necessarily fluent in the language of their workplace and face other barriers to connecting at work, creating turnover issues when they’re not able to communicate effectively. Anthill, which pitched on the Startup Battlefield stage at Disrupt, offers a non-app way for employers to communicate with workers — and vice versa — through text messages, the one sure-fire platform that reaches everybody and doesn’t let anyone fall through the cracks. “We knew as researchers if we wanted these folks to talk to us and stay in our studies we had to text them,” Clauson said. “And so we are super bullish on technology that meets people where they are, works within the fiber of how they already work and live their lives, and doesn’t force them to learn a new suite of technologies.” The idea is to give workers a way to access any information they could need — pay schedules, contact with a manager, taking a sick day — all through text message. And a way on the employer side to automate as much of that as makes sense, all while offering a full portal of resources without forcing people to download apps or jump through hoops that not everyone can manage. In the interest of making access to those resources more equitable, Anthill automatically translates its services into more than 100 languages — a feature that could also help employers retain workers who might be alienated by the lingua franca of the workplace. “A lot of us have family members who have not been able to participate in benefit adoption or knowing how to have any kind of outside of work community through their employer around all those critical things like tax season and schedules and just the basics — because language was a barrier,” Clauson said. “There’s a lot of folks who can work in English, but that doesn’t mean it’s their preferred language and it doesn’t mean that’s going to be the language that they can most successfully navigate their ability to work.” Anthill plans to focus on a handful of core industries out of the gate, including manufacturing, distribution (think Amazon warehouses) and agriculture. Kim and Clauson also see opportunities for connecting deskless workers with employers in retail and healthcare, but observe that those areas have a bit more tech already than some other sectors. “We really focused on individual-level needs [and] what they actually need is communication,” Kim told ZebethMedia. “Those workers, they actually need very simple things, but they need the answer right away,” Kim told ZebethMedia. While some employers have gone the route of using chatbots and apps, Anthill lets managers save recent answers to commonly asked questions and personalize the resources in a way that more tech-focused solutions might overlook. It’s probably difficult for knowledge workers or big tech companies to imagine, but Clauson says that the two modes of communication that Anthill replaces most frequently are AM radio followed by an old-fashioned corkboard. “We do try to stay focused within industry verticals. So we’re very focused right now on manufacturing workers inside of plants or distribution workers in distribution centers or truck drivers,” Clauson said. “That’s where we saw the biggest pain points and that’s where we’re focused first.” Anthill first opened in alpha in late 2020, with paid pilots and a beta version of the product the following year. The company launched a full version of the platform in 2022 and currently operates in over 300 job sites in the U.S., with global contracts in the pipeline slated for 2023. According to the company, large employers trying out Anthill often do a test run with a single distribution center or a cluster of regional sites and scale up from there. They can buy Anthill on a per-user, per-month basis, making it relatively straightforward to scale the platform up and out if it’s a good fit. The services are opt-in, not required, but Kim and Clauson have observed swift adoption that travels by word of

Circular Genomics uses RNA to stop depression meds being a guessing game • ZebethMedia

For many people who live with depression, medication is an important part of managing the condition. But knowing which will work for you can be a difficult months-long process. Circular Genomics claims its new form of genetic testing can identify which medications will work for a patient in a fraction of that time. As some of our readers no doubt already know — depression affects hundreds of millions, after all — finding the right medication is basically a crap shoot. Your provider picks one that they think meets your needs, then slowly ramps up the dose over a month or two, and if it doesn’t work, ramps it down again and tries a new one. If you’re lucky, the first one works; if not, it could be many months before you find a working dose — if it isn’t a resistant condition. And all that time you’re living with inadequately treated depression, possibly even exacerbated by the disruptive process of a constantly shifting drug regimen. Circular Genomics, which presented today as part of the Startup Battlefield at ZebethMedia Disrupt, is taking aim at this huge problem with a new testing method that relies on a molecule in our body we’ve known about for decades but only recently started paying attention to: circular RNA.   DNA, as we all know, encodes our genes using a base code; when it’s time to actually make things, that code is processed and it produces RNA, which more directly describes the proteins that will eventually be created, but is much easier to read than either DNA or the proteins themselves. The problem with RNA is that it degrades quickly, more or less by design: the ends of each strand are reactive and the whole thing starts getting unraveled by enzymes within a few hours. But sometimes those two ends join and form “circular RNA”: the same molecule, but it lasts much, much longer. “Circular types were discovered 5-10 years ago; we’ve known they existed since the 70s, but until deep sequencing technologies advanced we were never able to pull them out of the data,” explained Circular Genomics co-founder and president Alexander Hafez. “The stability increases substantially, you go from 18-24 hours to a week.” This matters because if you want to know what’s going on in the brain, RNA expression is your best bet — but you can’t extract it directly, and by the time blood carries it out of the brain, it’s already started to fall apart. DNA and protein analysis aren’t much help either. But with the advent of new sequencing tools, that’s all about to change. “Circular RNA is the first reliable biomarker that lets us look at brain conditions,” Hafez said. Depression is the first target, in particular what type of medication would likely work best for a person. The company has undergone two clinical studies so far: “We used blood samples, and got an idea of class response — for example, whether they would respond to an SSRI or not. Then we did another where we were able to look at whether a patient would respond to Zoloft specifically.” (Zoloft is a commonly prescribed antidepressant.) Having a starting place for what medication is mostly likely to work cuts out a huge amount of unnecessary care: not just the meds themselves but appointments, paperwork, insurance scuffles, risk of hospitalization, and so on. The all-inclusive cost of 6-12 months of care as someone works through the options is considerable, and that’s without reckoning with the more subjective costs of the process. Hafez did say that circular RNA is rapidly expanding its presence in the biotech world. “When we first started the company, there weren’t a lot of publications available; now it seems like every week there’s an article about how they’re useful biomarkers for cancers and other things.” Circular Genomics has a few patents pending, though, and are holding onto a some of the IP, like the actual identification process — this isn’t something anyone can just do with a sequencer and a bit of free time. The company is currently working on getting additional clinical testing done so the product can be confidently brought to market. But there are other applications on the horizon as well. Hafez said that they may also have located biomarkers for depression itself — something that could be immensely helpful. “Our society has a big stigma around depression diagnosis,” and mental illness in general, he said. But if depression, like so many other conditions, could be shown on a simple blood test, it would help remove that stigma. People who have trouble accepting depression as the cause of their or another’s experiences — or stubborn insurance companies, for that matter — may find a + sign on a blood test more convincing. Of course that opens the door to requiring biological markers as proof of mental illness, but we can cross that bridge when we get there. In the meantime the company is still working out the best way to get the technology in patients’ hands. At first it may be an optional test not covered by insurance, with a cost around $1,000. Obviously that’s not accessible to everyone, but like many new approaches not yet qualified for reimbursement, there are grants and other offsets that can be brought into play if the benefits are substantial.

Omneky uses AI to generate social media ads • ZebethMedia

Meet Omneky, a startup that leverages OpenAI’s DALLE-2 and GPT-3 models to generate visuals and text that can be used in ads for social platforms. The company wants to make online ads both cheaper and more effective thanks to recent innovations in artificial intelligence and computer vision. Omneky is participating in Startup Battlefield at ZebethMedia Disrupt 2022. While many fields have been automated in one way or another, creating ads is still mostly a manual process. It takes a lot of back and forth between a creative team and the person in charge of running online ad campaigns. Even when you manage to reach a final design, the new ads might not perform as well as expected. You often have to go back to the drawing board to iterate and create more ads. Omneky aims to simplify all those steps. It starts with a nice software-as-a-service platform that centralizes all things related to your online advertising strategy. After connecting Omneky with your accounts on Facebook, Google, LinkedIn and Snapchat, the platform pulls performance data from your past advertising campaigns. From this analytics dashboard, you can see how much you’re spending, how many clicks you’re getting, the average cost per click and more. But it gets more interesting once you start diving a bit deeper. Omneky lists your top-performing and worst-performing images and text used in your ads. Customers can click on individual ads to see more details. Omneky automatically adds tags to each ad using computer vision and text analysis. The result is a dashboard with useful insights, such as the dominant color you should use, the optimal number of people in the ad and some keywords that work well in the tagline. This data will be used to generate new ads. Customers write a prompt and generate new visuals using DALLE-2. Omneky also helps you with those prompts as it also uses GPT-3 to generate prompts based on top-performing keywords from past campaigns. Customers then get dozens of different AI-generated images that can be used in online ads. Similarly, Omneky can generate ad copy for the text portion of your ads. If you have a strong brand identity, Omneky can take this into account. On the platform, customers can upload digital assets and historical ads so that the platform acts as the central repository. “Customers can upload the brand guidelines, the font, the logo. All of this is integrated into our AI to generate content that is on brand,” Omneky founder and CEO Hikari Senju told me in a call before ZebethMedia Disrupt. Of course, some images and text don’t work well for one reason or another. That’s why Omneky doesn’t run any ad campaign without the customer’s approval. Team members can add comments, provide feedback and request approval from the platform directly. As soon as customers approve a new ad, it is automatically uploaded and displayed on social platforms — Facebook, Google, LinkedIn and Snapchat. After that, you are back to square one. You can track the performance of your new ads from the analytics dashboard, iterate and improve your ad performance. The company charges a subscription fee that varies depending on the number of integrations with social platforms that you want to use. Omneky’s long-term vision expands beyond advertising. There’s a lot of data involved with online ads, that’s why it’s easy to automate some of the steps needed to run an online ad campaign. But the startup thinks it could apply the same methodology to other products, such as AI-generated landing pages. If you extrapolate even more, it’s clear that AI-generated content will cause a revolution in the martech and adtech industries — and Omneky plans to participate in that revolution. Image Credits: Omneky

Marc Lore shares exclusive details on Jump Platforms, his stealth sports ticketing startup • ZebethMedia

Today at ZebethMedia Disrupt, serial entrepreneur Marc Lore disclosed exclusive details about a new dynamic ticketing startup, still in stealth, that he founded with former New York Yankee all-star Alex Rodriguez. Called Jump Platforms, the company will sell access to seats that free up when people leave midway through a game. Fans already at the game are alerted when better seats become available. Pricing starts high and drops depending on demand in a reverse auction format.  Lore, who co-owns the NBA’s Minnesota Timberwolves with A-Rod, has applied for a patent that is still pending. He said he started looking into dynamic ticketing years ago when he was attending various sporting events.  “I just felt like wow, why are all the seats empty close to the field or close to the arena? And why, when people leave, like when they leave the baseball game in the eighth inning, and all these incredible seats — why do they have people that don’t let anyone go down?” he said, referring to event security staff. “Nobody’s sitting there.” “So I thought, why couldn’t you — this was the patent — dynamically in real time make these seats available so that people could could jump to any new seat so they would always be filled in. Everybody from the top would naturally come down because there would be a reverse auction,” Lore said. “I call it dynamic real-time ticketing. There’s lots of other things you can do with that technology.” Lore assigned the patent to the company and is an investor in the startup. Jump is still in stealth mode, according to CEO Jordy Leiser’s LinkedIn profile. According to incorporation papers filed in Delaware, the company was founded in August 2021.

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